Procavea Biotech AG

First-in-class adrenal siRNA delivery system

Procavea Biotech AG is an ETH Zurich spin-off advancing a first-in-class siRNA delivery platform. While standard systems are restricted to liver delivery, Procavea’s proprietary OP protein cage enables extrahepatic delivery, specifically targeting the adrenal cortex - a region previously unreachable by RNAi. The lead program, PCV-001, targets Primary Aldosteronism, converting a validated pathway into a durable, quarterly-dosed therapy. Procavea employs a hybrid business model: developing an internal adrenal pipeline while partnering with pharma to enable delivery to tissues like the CNS and kidney.

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Milestone

09.05.2023

Innosuisse Innovation Project

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Venture Kick

Venture Kick supports potential entrepreneurs with start capital up to CHF 150'000 as well as hands-on execution support and access to a nationwide network of investors and experts in the startup field. Multiple times per year, 8 selected projects get the opportunity to present their business ideas in front of a panel. The 5 most promising projects enter the support process. After 9 months at the latest, the startups incorporate and enter the market. Since 2007, Venture Kick has invested over CHF 58 million in over 1111 projects.

Website

Procavea Biotech AG

First-in-class adrenal siRNA delivery system

Headquarter:
Zürich ETH-Hönggerberg

Foundation Date:
February 2024

Technology:

  • Biotech

Sectors:

  • Biotech
  • Cardiovascular
  • Drug development platforms
  • Drug discovery

Support received

  • Support venturekick