MechaGel

Developed as an EPFL initiative, MechaGel addresses the challenges of traditional joint repair with an innovative, intrinsically adhesive hydrogel technology designed to treat cartilage damage. Injected via a minimally invasive, single-surgery procedure, the biocompatible, biomimetic polymeric gel fills the contour of any joint defect. It is then rapidly cured in place using blue light activation. Utilizing a dual chemical-mechanical network inspired by marine bioglues, the hydrogel achieves superior tissue integration and lateral adhesion without needing extra surface treatments. This structure prevents further joint degeneration and acts as a transient, load-bearing scaffold that naturally degrades as the patient's cells migrate to regenerate healthy cartilage.