BLEEDnFIRE Therapeutics AG

RNAi-based therapies to treat bleeding disorders

BLEEDnFIRE Therapeutics is a biotech company developing first-in-class RNAi therapies to rebalance hemostasis in severe bleeding disorders. Our lead program, BnF-001, selectively targets Protein S to restore thrombin generation and provide durable bleed protection without factor replacement, addressing key limitations of current therapies across disorders such as von Willebrand disease, Glanzmann thrombasthenia and hemophilia. Beyond bleeding control, the approach has the potential to improve long-term joint and bone health, a major source of morbidity in these patients.

BLEEDnFIRE has secured a strong intellectual property position, including granted patents and additional patent applications. The team combines complementary expertise in hem

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Milestone

19.12.2025

4th Patent

Milestone

20.11.2025

Incorporation BLEEDnFIRE Therapeutics AG - Bern

Milestone

14.10.2025

Innosuisse Core coaching - Phase II validated

Milestone

16.06.2025

siRNA screening finalized/leads candidates selected

Milestone

30.03.2025

In vitro, in vivo & ex vivo PoC confirmed

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Venture Kick

Venture Kick supports potential entrepreneurs with start capital up to CHF 150'000 as well as hands-on execution support and access to a nationwide network of investors and experts in the startup field. Multiple times per year, 8 selected projects get the opportunity to present their business ideas in front of a panel. The 5 most promising projects enter the support process. After 9 months at the latest, the startups incorporate and enter the market. Since 2007, Venture Kick has invested over CHF 58 million in over 1111 projects.

Website

UNIBE Spin-off

Website

BLEEDnFIRE Therapeutics AG

RNAi-based therapies to treat bleeding disorders

Headquarter:
Bern

Foundation Date:
November 2025

Technology:

  • Biotech

Sectors:

  • Biotech

Support received

  • Support venturekick