ASTRA Therapeutics AG

ASTRA Therapeutics is a drug development company generating new therapeutic drug candidates effective across the whole range of parasitic diseases by targeting a highly conserved parasite protein: Tubulin. This protein is essential to cell division in all eukaryotic cells, meaning perturbing its function is highly toxic for all cells - a property that has found wide application in anti-cancer drugs. We have perfected the design of sequence-specific tubulin inhibitors with atomic-scale drug engineering to specifically inhibit parasite tubulin while staying harmless to their hosts. We call these species-specific parasite inhibitors Parabulins. We are focusing on Parabulins targeting parasite pathogens of humans, veterinary medicine, and agriculture.