OptimalPSI AG

Topology optimization for patient-specific spinal implants.

With approximately 400,000 patients undergoing spinal fusion surgery annually in the U.S, the procedure faces a critical complication post-operatively: implant subsidence. This port-operative complication, where the implant breaks through the vertebral endplates due to insufficient bone strength, affects 51% of patients. In our innovative approach, we use a new topology optimization method (patent pending) to design a patient-specific implant that reduces the risk of subsidence by 90% compared to currently used implants. The founding team consists of two PhD's from ETH Zurich. The potential revenue of our technology in our niche market in the US amounts to 1.73B USD, annually.

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Venture Kick

Venture Kick supports potential entrepreneurs with start capital up to CHF 150'000 as well as hands-on execution support and access to a nationwide network of investors and experts in the startup field. Multiple times per year, 8 selected projects get the opportunity to present their business ideas in front of a panel. The 5 most promising projects enter the support process. After 9 months at the latest, the startups incorporate and enter the market. Since 2007, Venture Kick has invested over CHF 58 million in over 1111 projects.

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OptimalPSI AG

Topology optimization for patient-specific spinal implants.

Headquarter:
Basel

Foundation Date:
September 2025

Technology:

  • Medtech

Sectors:

  • 3D Printing
  • Digital Health
  • Machine Learning / AI
  • Medical devices
  • Medtech
  • Orthopedics
  • Software
  • Surgery

Support received

  • Support venturekick